Adverse Physiological or Toxicological Effects

Adverse physiological or toxicological effects are considered to be evidence of cardiac sensitization, for the purposes of approving halocarbon fire-extinguishing agents in accordance with MSC/Circ.848 and MSC.1/Circ.1267.

Source: IMO MSC.1/Circ.1316, Guidelines on determining the no observed adverse effect level (NOAEL) and lowest observed adverse effect level (LOAEL) values for halocarbon fire-extinguishing agents, 10 June 2009, International Maritime Organization. Regulatory Guidance

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