Definition(s)
Significant change
A significant change is likely to be one that changes the basis on which the safety case was accepted. In relation to a safety management system, “significant change” means a change to the whole of, or a major part of, the safety management system that would warrant a change to the description of the SMS in the safety case.
Source: NOPSEMA Guidance note: Safety Case Lifecycle Management, N04300-GN0087, Australia, Revision 5, December 2012. Regulatory Guidance